Chpt 5; pp. 75-101
Autonomic Drugs
Review Questions 

1. Where are the two main divisions of the Nervous System?
2. What are the main functions of the CNS?
3. What composes the CNS?
4. What is the main function of the PNS?
5. What are the two main divisions of the PNS?
6. What is the main function of the SNS?
7. What is the main function of the ANS?
8. What are the two main divisions of the ANS?
9. Each division of the ANS contains what 3 things?
10. To remember what the PANS does and the neurotransmitter involved, what is the memory link?
11. List the main effects of the PANS.
12. List the main effects of the SANS.
13. What is the memory link to remember the SANS functions?
14. What 3 major neurotransmitters are found in the ANS?
15. Define neurotransmitter.
16. Drugs can modify ANS activity by altering any what 5 events associated with neurotransmitters?
17. What is the neuroeffector site for the SNS?
18. What is the neuroeffector site for the PANS?
19. What is the neuroeffector site for the SANS?
20. What is the major neurotransmitter for the SNS?
21. What is the major neurotransmitter for the PANS?
22. What is the major neurotransmitter for the SANS?
23. What is the neuroreceptor for the SNS?
24. What are the nueroreceptors for the PANS?
25. What are the neuroreceptors for the SANS?
26. Nerves that receive (Receptors) acetylcholine are termed what?
27. Nerves that receive (Receptors) norepinephrine or epinephrine are termed what?
28. Drugs that act at the location where ACh is released as the neurotransmitter are termed what?
29. Drugs that act at the location where norepinephrine is released as the neurotransmitter are termed what?
30. The prefix used when drug acts at location PANS acts is what?
31. The prefix used when drug acts at location SANS acts is what?
32. The suffix used when drug acts at location where a division of the ANS acts and drug produces SAME effect as the neurotransmitter is termed what?
33. What is another name for –mimetic?
34. Suffixes used when drug acts at location where a division of the ANS acts and BLOCKS the action of the neurotransmitter are what?
35. What is another name for blocker?
36. What drug categories stimulate or mimic PANS?
37. What drug categories stimulate or mimic SANS?
38. What drug categories inhibit/block the effect of PANS?
39. What drug categories inhibit/block the effect of SANS?
40. What is the principle neurotransmiter (mediator) in the PANS?
41. In order for ACh to be an effective mediator, it must fit both physically and chemically at the?
42. What receptors can ACh bind to?
43. What is the mechanism of action for direct (Choline ester) agents?
44. What is the mechanism of action for indirect (Anicholinesterase) agents?
45. How do Cholinergic (Parasympathomimetic) agents affect the GI system?
46. How do Cholinergic (Parasympathomimetic) agents affect the eyes?
47. Large doses of Cholinergic (Parasympathomimetic) agents may cause what adverse reactions?
48. An overdose of Cholinergic (Parasympathomimetic) agents is treated with what?
49. List the 6 Cholinergic (Parasympathomimetic) relative contraindications.
50. Acetylcholine is used for what?
51. Methacholine (Provocholine) is used for what?
52. Bethanechol (Urecholine) is used for what?
53. Carbachol (Miostat) is used for what?
54. Pilocarpine (Adsorbocarpine is used for what?
55. Edrophonium (Tensilon) is used for what?
56. Neostigmine (Prostigmin) is used for what?
57. Pyridostigmine (Mestinon is used for what?
58. Physostigmine (Eserine) is used for what?
59. Malathion and Parathion are used for what?
60. Sarin and tabun are used for what?
61. What is the mechanism of action of Anticholinergic (Parasympatholytic) Agents (Muscarinic Antagonists)?
62. What are the main uses of the Anticholinergics? (3)
63. How do Anticholinergic (Parasympatholytic) agents affect the CNS?
64. How do Anticholinergic (Parasympatholytic) agents affect the Exocrine glands?
65. How do Anticholinergic (Parasympatholytic) agents affect the smooth muscle?
66. How do Anticholinergic (Parasympatholytic) agents affect the eye?
67. How do Anticholinergic (Parasympatholytic) agents affect the CVS?
68. List a minimum of 4 adverse reactions associated with anticholinergic agents.
69. List the 5 signs of toxicity of anticholinergic agents.
70. List 4 anticholinergic (Parasympatholytic) contraindications.
71. Atropine (Atripison) is used for what?
72. Scopolamine is used for what?
73. Methantheline (Banthine) is used for what?
74. Dicyclomine (Bentyl) and Propantheline (Pro-Banthine) are used for what?
75. Bentropine mesylate (Cogentin) is used for what?
76. What are 4 possible Anticholinergic (Parasympatholytic) harmful drug interactions?
77. What is the mechanism of action for the Neuromuscular Blocking Drugs?
78. List a Nondepolarizing (competitive) Blocker and what it is used for.
79. List a Depolarizing Agent and what it is used for.
80. What are the major neurotransmitters of the SANS?
81. What is epinephrine’s mechanism of action?
82. What is amphetamine’s mechanism of action?
83. What is ephedrine’s mechanism of action?
84. What two products are involved with the metabolism of epinephrine/NE?
85. Stimulation of the alph receptors produces what?
86. Stimulation of the Beta 1 receptors produces what?
87. Stimulation of the Beta 2 receptors produces what?
88. How do Adrenergic (Sympathomimetic) agents affect the CNS?
89. How do Adrenergic (Sympathomimetic) agents affect the CVS?
90. How do Adrenergic (Sympathomimetic) agents affect the eyes?
91. How do Adrenergic (Sympathomimetic) agents affect the respiratory system?
92. How do Adrenergic (Sympathomimetic) agents affect the metabolic system?
93. How do Adrenergic (Sympathomimetic) agents affect the salivary glands?
94. List the Adrenergic (Sympathomimetic) Adverse Reactions.
95. List the Adrenergic (Sympathomimetic) Contraindications.
96. List several of the Adrenergic (Sympathomimetic) uses.
97. What is Epinephrine (Adrenalin) used for?
98. What is Phenylephrine [fen-ill-EF-rin] (Neo-Synephrine) used for?
99. What is Levonordefrin [lee-voe-nor-DEF-rin] (Neo-Cobefrin) used for?
100. What is Isoproerenol [eye-soe-proe-ter-e-nole] (Isuprel) used for?
101. What is Ephedrine/Pseudoephedrine (Sudafed) used for?
102. What is Dopamine [DOE-pa-meen] (Intropin) used for?
103. What is Dipivefrin [dye-PIV-e-frin] (Propine) used for?
104. What is Albuterol (Proventil, Ventolin) used for?
105. List a few agents used to treat Attention Deficit disorder.
106. List a few agents used for weight loss.
107. What is the main use for Adrenergic Blocking Agents (Antagonists)
108. Define Epinephrine Reversal
109. Give 3 examples of Alpha Adrenergic blocking agents.
110. Generic names that end in –olol are what agents?
111. Give an example of a Nonselective (ß₁ and ß₂₎  agent..
112. Give an example and the benefit of a Selective (Specific) – blocking agent.
113. Give an example of a Alpha and Beta Adrenergic Blocking Agent.
114. What is the mechanism of Adrenergic Neuronal Agonists and Antagonists
115. What OTC products should be avoided when taking ANS drugs?